drugset / Trial / NCT02631772

LIVE-C-Free: Early and Late Treatment of Hepatitis C With Sofosbuvir/Ledipasvir in Liver Transplant Recipients

NCT02631772

Phase 4 Completed 32 enrolled Medical University of South Carolina
RandomizedParallel-groupOpen-labelTreatment

Summary

The predominant remaining questions for post-transplant treatment of Hepatitis C virus (HCV) in the DAA (direct acting anti-virals) era are whether a ribavirin-free regimen is possible and whether pre-emptive treatment is now a potential option to prevent long-term damage to the allograft. Our aim is to provide answers to these primary questions with our multicenter, prospective, randomized, open-label intent-to-treat phase IV study

Timeline

Start
2016-06-01
Primary completion
2018-05-30
Completion
2018-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ribavirin Small molecule
Subject Sofosbuvir/Ledipasvir Unknown