Effects of a Supplement Derived From Palm Oil on Cholesterol Levels in the Blood
Summary
Elevated blood cholesterol, and particularly LDL cholesterol, is a risk factor for heart disease. Tocotrienols are naturally-occurring compounds in foods that may have beneficial effects on blood cholesterol. Tocotrienols are members of the vitamin E family, and are found in barley, oats, rye, coconut oil and rice bran oil, but the richest source of tocotrienols is palm oil. Certain of these tocotrienols have been shown to be effective in lowering LDL (or 'bad') cholesterol, with no adverse effects on the HDL (or 'good') cholesterol. The purpose of this study is to determine the effects of a palm-oil derived tocotrienol supplement on blood cholesterol, and particularly LDL cholesterol, in individuals who are taking statins, and have either elevated or normal cholesterol levels. Study subjects will consume a palm-oil derived supplement of tocotrienol for 3 months to determine its effects on LDL cholesterol.
Timeline
- Start
- 2011-03-22
- Primary completion
- 2015-11-13
- Completion
- 2015-11-13
Outcome
Outcome not reported
Stopped (Enrollment): “Unable to obtain supplement for this study. Unable to recruit.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Gamma Delta Tocotrienols | Small molecule | 63 mg | Oral |
| Comparator | Gamma Delta Tocotrienols | Small molecule | 127 mg | Oral |