Methocarbamol in Treatment of Muscle Cramps in Cirrhotic Patients

Summary

Muscle cramps markedly affect the quality of life in cirrhotic patients with no highly effective drug. Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. The mechanism of action of methocarbamol is currently unknown, but may involve the inhibition of carbonic anhydrase. Methocarbamol has a high therapeutic index, i.e. a wide range of safe and effective dosages.

Timeline

Start

2017-04-01

Primary completion

2020-12

Completion

2020-12

Drugs

Indications