drugset / Trial / NCT02642900

Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers

NCT02642900

Phase 4 Completed 22 enrolled University of Sao Paulo
RandomizedParallel-groupSingle-blindTreatment

Summary

Candida albicans is the most prevalent species in denture-related stomatitis (DS). There are several treatment options for this condition, including the use of antifungal agents such as nystatin and miconazole. The side effects and the increasing number of resistant species caused by the use of these drugs encourage the development of alternative therapies. Photodynamic Therapy (PDT) has been used as a promising treatment of stomatitis. In this randomized clinical trial, the effectiveness of PDT was evaluated. Patients in this study were allocated to two groups. One group was treated with nystatin, and the other group was treated with PDT.

Timeline

Start
2009-07
Primary completion
2011-02
Completion
2011-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Nystatin Unknown 100000 iu Topical

Indications