drugset / Trial / NCT02644252
Tocotrienol as a Nutritional Supplement in Patients With Advanced Lung Cancer
RandomizedParallel-groupDouble-blindTreatment
Summary
There is a need for improving the effect of first-line chemotherapy for lung cancer patients, preferably by using an approach with none or very few side effects. In this trial the investigators incorporate δ-tocotrienol/placebo as a nutritional supplement on top of standard chemotherapy for patients with advanced non-small cell lung cancer.
Timeline
- Start
- 2016-01
- Primary completion
- 2019-05-09
- Completion
- 2021-01-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tocotrienol | Small molecule | 300 mg | — |
| Background | Carboplatin | Small molecule | — | — |
| Background | Cisplatin | Other / unclassified | 75 mg/m2 | — |
| Background | Vinorelbine | Small molecule | 25 mg/m2 | — |
| Background | Vinorelbine | Small molecule | 30 mg/m2 | — |
| Background | Vinorelbine | Small molecule | 50 mg/m2 | — |
| Background | Vinorelbine | Small molecule | 60 mg/m2 | — |