drugset / Trial / NCT02648438

A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects

NCT02648438

Phase 1 Completed 30 enrolled AstraZeneca
RandomizedParallel-groupOpen-labelBasic science

Summary

This is an open-label,partially randomized, four-period study in healthy male subjects to assess the bioavailability and pharmacokinetics of a single dose of AZD7594 when administered intravenously, orally and inhaled via two different dry powder inhalers (DPIs) and a pressurized meter-dose inhaler (pMDI)

Timeline

Start
2016-01-12
Primary completion
2016-06-01
Completion
2016-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject VELSECORAT Other / unclassified 150 ug Intravenous
Subject VELSECORAT Other / unclassified 400 ug Intravenous
Subject VELSECORAT Other / unclassified 1200 ug Intravenous