drugset / Trial / NCT02650609
Treatment of Chronic Subdural Hematoma by Corticosteroids
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Chronic subdural hematomas are a frequent neurosurgical pathology in the elderly. Gold standard is surgical evacuation of these hematomas. Physiopathology of chronic subdural hematoma involves numerous inflammatory processes which could be inhibited by steroids.
Timeline
- Start
- 2016-06-24
- Primary completion
- 2019-03-20
- Completion
- 2020-03-20
Publications
- Fougerou-Leurent C, Forteau L, Perrot-Loyer M, Renault A, Brion M, Mouchel C, Rousseau C, Marion E, Cochennec S, Ganivet A, Gervais ML, Fin L, Laviolle B. Evaluating the Environmental Impact of Clinical Research: A Full Life Cycle Analysis of a French Academic Randomised Clinical Trial. Fundam Clin Pharmacol. 2026 May;40(3):e70086. doi: 10.1111/fcp.70086.
- Henaux PL, Le Reste PJ, Laviolle B, Morandi X. Steroids in chronic subdural hematomas (SUCRE trial): study protocol for a randomized controlled trial. Trials. 2017 Jun 5;18(1):252. doi: 10.1186/s13063-017-1990-8.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylprednisolone | Other / unclassified | 1 mg/kg | Oral |
Indications
No indication recorded.