drugset / Trial / NCT02654236
Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling
Completed
30 enrolled
Suthat Liangpunsakul
Intercept Pharmaceuticals · collabNational Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
RandomizedParallel-groupQuadruple-blindOther
Summary
The main purpose of this study is to see whether heavy drinking will interfere with a specific pathway, called FXR signaling in the liver. The abnormality of this pathway may lead to liver injury in some patients who drink heavily.
Timeline
- Start
- 2016-04
- Primary completion
- 2019-09
- Completion
- 2019-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Obeticholic Acid | Small molecule | 10 mg | Oral |