drugset

drugset / Trial / NCT02660177

Pharmacokinetics of Intravenous Metamizole in Children Less Than 6 Years Old

NCT02660177 ↗

Phase 2 Completed 33 enrolled University Children's Hospital Basel

NaSingle-groupOpen-labelOther

Summary

This study aims to assess the PK parameters of metamizole following a single IV administration of metamizole in children less than 6 years of age.

Timeline

Start: 2016-04
Primary completion: 2017-12
Completion: 2017-12

Publications

Ziesenitz VC, Rodieux F, Atkinson A, Borter C, Bielicki JA, Haschke M, Duthaler U, Bachmann F, Erb TO, Gurtler N, Holland-Cunz S, van den Anker JN, Gotta V, Pfister M. Dose evaluation of intravenous metamizole (dipyrone) in infants and children: a prospective population pharmacokinetic study. Eur J Clin Pharmacol. 2019 Nov;75(11):1491-1502. doi: 10.1007/s00228-019-02720-2. Epub 2019 Aug 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Metamizole	Unknown	10 mg/kg	Intravenous

Indications

No indication recorded.