Safety and TDM of Continuous Infusion Vancomycin Through Continuous Renal Replacement Therapy Solution

Summary

The purpose of this investigation is to evaluate the safety of delivering continuous infusion (CI) vancomycin in pediatric CRRT by utilizing CI via by mixing the vancomycin into the CRRT solution(s). The secondary objectives are to describe the ability to achieve therapeutic vancomycin concentrations by utilizing this new delivery technique. Primary Objectives: To determine whether delivering continuous infusion vancomycin mixed into the CRRT solution can maintain therapeutic levels of drug in patients being treated for proven or suspected Gram-positive bacterial infections.

Timeline

Start

2017-01

Primary completion

2021-12

Completion

2022-12

Drugs

Indications