drugset / Trial / NCT02664961

Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN)

NCT02664961

Phase 2 Terminated 3 enrolled Tracon Pharmaceuticals Inc.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of the study is to determine the overall response rate of single agent TRC105 and the combination of TRC105 and bevacizumab in patients with refractory GTN (including choriocarcinoma, placental site trophoblastic tumor (PSTT), and epithelioid trophoblastic tumor (ETT)). Up to 30 patients will be treated.

Timeline

Start
2016-03
Primary completion
2018-04
Completion
2018-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody
Subject Carotuximab Monoclonal antibody