drugset / Trial / NCT02675374

Hemodynamic Instability Prevented With Polaramine® Infusion Before Extracorporeal Circulation

NCT02675374

Phase 3 Terminated 18 enrolled University Hospital, Bordeaux
RandomizedParallel-groupTriple-blindPrevention

Summary

This single-institution randomized controlled trial prospective will enrolled 48 patients scheduled for an aortic valve replacement. The objective of the present investigation is to determine the role of Polaramine® on reducing hemodynamic instability after separation from cardiopulmonary bypass (CPB) during cardiac surgery. Our hypothesis is that Polaramine® play an important role reducing dysfunction of the autonomic nervous system and hemodynamic stability after separation from CPB.

Timeline

Start
2016-06-05
Primary completion
2017-07-18
Completion
2017-07-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexchlorpheniramine Unknown 10 mg Intravenous

Indications

No indication recorded.