drugset / Trial / NCT02675374
Hemodynamic Instability Prevented With Polaramine® Infusion Before Extracorporeal Circulation
RandomizedParallel-groupTriple-blindPrevention
Summary
This single-institution randomized controlled trial prospective will enrolled 48 patients scheduled for an aortic valve replacement. The objective of the present investigation is to determine the role of Polaramine® on reducing hemodynamic instability after separation from cardiopulmonary bypass (CPB) during cardiac surgery. Our hypothesis is that Polaramine® play an important role reducing dysfunction of the autonomic nervous system and hemodynamic stability after separation from CPB.
Timeline
- Start
- 2016-06-05
- Primary completion
- 2017-07-18
- Completion
- 2017-07-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexchlorpheniramine | Unknown | 10 mg | Intravenous |
Indications
No indication recorded.