Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations

Summary

The study will investigate the ability of a new PET tracer, 18F-AV-1451, to detect depositions of a protein, called tau, in the brains of people with a mutation in the tau gene that causes deposition of the protein, and in people without the mutation. Up to three 18F-AV-1451 scans will be performed (one per year) on control subjects without MAPT mutations, presymptomatic mutation carriers, and symptomatic mutation carriers.

Timeline

Start

2016-04

Primary completion

2018-11-25

Completion

2018-11-25

Drugs

Indications