Nasal Versus Oral Midazolam Sedation in Routine Pediatric Dental Care

Completed 70 enrolled Hadassah Medical Organization

RandomizedParallel-groupSingle-blindTreatment

Summary

The general objective of the study is to compare the efficacy of administering midazolam orally as syrup versus nasally with nasal atomizer. The specific objectives are to measure: 1) acceptability of the medication, 2) effect on behavior, 3) time of onset, 4) maximum working time.

Timeline

Start: 2017-03-28
Primary completion: 2020-12-15
Completion: 2020-12-15

Publications

Fux-Noy A, Saadi Q, Shmueli A, Halperson E, Ram D, Moskovitz M. Parents' satisfaction and children's acceptance of nasal compared to oral midazolam for sedation in two consecutive pediatric dental treatments: a randomized controlled study. Front Dent Med. 2023 Dec 21;4:1296823. doi: 10.3389/fdmed.2023.1296823. eCollection 2023.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Midazolam	Small molecule	0.2 mg/kg	Oral
Comparator	Midazolam	Small molecule	0.5 mg/kg	Oral

Indications

No indication recorded.