Combined Treatment of Minocycline and Lovastatin to Treat Individuals With Fragile X Syndrome

Summary

The purpose of this study is to determine whether Lovastatin, Minocycline and the combination Lovastatin/Minocycline are effective in treating behavioral symptoms in Fragile X individuals.

Timeline

Start

2016-03

Primary completion

2017-10

Completion

2017-11

Publications

• Morin-Parent F, Champigny C, Cote S, Mohamad T, Hasani SA, Caku A, Corbin F, Lepage JF. Neurophysiological effects of a combined treatment of lovastatin and minocycline in patients with fragile X syndrome: Ancillary results of the LOVAMIX randomized clinical trial. Autism Res. 2024 Sep;17(9):1944-1956. doi: 10.1002/aur.3222. Epub 2024 Sep 9.

Drugs

Indications