drugset / Trial / NCT02684461
Phase II Trial of Sequential Consolidation With Pembrolizumab Followed by Nab-paclitaxel
Phase 2
Completed
20 enrolled
UNC Lineberger Comprehensive Cancer Center
Merck Sharp & Dohme LLC · collab
RandomizedFactorialOpen-labelTreatment
Summary
The purpose of this research study is to test the effectiveness of three treatment arms that are designed to improve survival in patients with non-small cell lung cancer. Eligible subjects could be randomized to four (4) cycles of chemotherapy followed by immunotherapy, or immunotherapy followed by chemotherapy, or four cycles of chemotherapy plus immunotherapy.
Timeline
- Start
- 2016-09-13
- Primary completion
- 2021-11-19
- Completion
- 2021-11-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Nab-paclitaxel | Small molecule | 100 mg/m2 | — |
| Comparator | Pembrolizumab | Monoclonal antibody | 200 mg | — |