drugset / Trial / NCT02687165

Uncovering Neural and Immune Mechanisms of Chronic Pain in Post Treatment Lyme Syndrome

NCT02687165

Terminated 4 enrolled New York State Psychiatric Institute
RandomizedFactorialDouble-blindTreatment

Summary

This study will investigate (a) neural and immune mechanisms underlying chronic pain in PTLS by comparing a group of PTLS patients and healthy participants on brain imaging, sensory, and immune markers; and (b) assess change in pain, brain imaging (fMRI and MRS), sensory, and immune markers in response to a combination of SNRI and glutamatergic treatment for chronic pain in PTLS (Milnacipran and D-cycloserine).

Timeline

Start
2016-01-16
Primary completion
2017-01-16
Completion
2017-01-16

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cycloserine Small molecule
Comparator Milnacipran Other / unclassified