drugset / Trial / NCT02687165
Uncovering Neural and Immune Mechanisms of Chronic Pain in Post Treatment Lyme Syndrome
RandomizedFactorialDouble-blindTreatment
Summary
This study will investigate (a) neural and immune mechanisms underlying chronic pain in PTLS by comparing a group of PTLS patients and healthy participants on brain imaging, sensory, and immune markers; and (b) assess change in pain, brain imaging (fMRI and MRS), sensory, and immune markers in response to a combination of SNRI and glutamatergic treatment for chronic pain in PTLS (Milnacipran and D-cycloserine).
Timeline
- Start
- 2016-01-16
- Primary completion
- 2017-01-16
- Completion
- 2017-01-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cycloserine | Small molecule | — | — |
| Comparator | Milnacipran | Other / unclassified | — | — |