drugset / Trial / NCT02692157

NT-814: Evaluation of Its Ability to Alter the Abuse Liability of Oxycodone in an Exploratory Clinical Study

NCT02692157

RandomizedCrossoverDouble-blindBasic science

Summary

Healthy adult men who abuse opioids and are physically dependent on them will be invited to participate in a study to examine the ability of NT-814, a neurokinin (NK) antagonist at the 1 and 3 receptor subtypes, to alter the abuse liability of oxycodone.

Timeline

Start
2016-02
Primary completion
2017-07-20
Completion
2018-09-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Elinzanetant Small molecule 50 mg Oral
Comparator Elinzanetant Small molecule 100 mg Oral
Comparator Elinzanetant Small molecule 200 mg Oral

Indications