drugset / Trial / NCT02692157
NT-814: Evaluation of Its Ability to Alter the Abuse Liability of Oxycodone in an Exploratory Clinical Study
Phase 1/2
Withdrawn
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA) · collab
RandomizedCrossoverDouble-blindBasic science
Summary
Healthy adult men who abuse opioids and are physically dependent on them will be invited to participate in a study to examine the ability of NT-814, a neurokinin (NK) antagonist at the 1 and 3 receptor subtypes, to alter the abuse liability of oxycodone.
Timeline
- Start
- 2016-02
- Primary completion
- 2017-07-20
- Completion
- 2018-09-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Elinzanetant | Small molecule | 50 mg | Oral |
| Comparator | Elinzanetant | Small molecule | 100 mg | Oral |
| Comparator | Elinzanetant | Small molecule | 200 mg | Oral |