drugset / Trial / NCT02695745

Experimental Biomarker Study for Pain Thresholds

NCT02695745

Phase 1 Completed 37 enrolled Purdue Pharma LP
RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to characterize the heat pain tolerance threshold (HPTolTr) in primary hyperalgesic skin after topical capsaicin application, and to assess heat pain and mechanical thresholds (eg, pressure pain, stimulus-response) following skin sensitization by UVB (ultraviolet B) irradiation and topical capsaicin.

Timeline

Start
2011-09
Primary completion
2012-01
Completion
2012-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Celecoxib Other / unclassified 400 mg Oral
Subject V116517 Unknown 300 mg Oral
Background Capsaicin Small molecule 1 % Topical

Indications

No indication recorded.