drugset / Trial / NCT02699008

High On-treatment Platelet Reactivity Identified by Multiple Platelet Function Assay

NCT02699008

Completed 477 enrolled Wuhan Asia Heart Hospital
RandomizedSingle-groupOpen-labelTreatment

Summary

High on-treatment platelet reactivity to adenosine diphosphate was a important reason to cause ischemic events in antiplatelet therapy. Using single testing to definite HPR may miss the "true HPR" or over estimate HPR, which may lead to randomized trials failed. It is not known whether combined multiple platelet function testing could assist to ensure"ture"HPR and improve clinical outcomes.

Timeline

Start
2014-01
Primary completion
2015-08
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Clopidogrel Small molecule
Comparator Ticagrelor Small molecule