drugset / Trial / NCT02701634

Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD)

NCT02701634

Phase 2 Terminated 66 enrolled Gilead Sciences
RandomizedParallel-groupDouble-blindTreatment

Summary

The primary objective of this study is to evaluate the effect of entospletinib (ENTO) on the best overall response rate in adults with chronic graft versus host disease (cGVHD) who are currently receiving systemic corticosteroids as part of first-line therapy for cGVHD.

Timeline

Start
2016-05-27
Primary completion
2017-12-19
Completion
2018-03-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Entospletinib Small molecule 200 mg Oral
Subject Entospletinib Small molecule 400 mg Oral