drugset / Trial / NCT02701634
Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD)
RandomizedParallel-groupDouble-blindTreatment
Summary
The primary objective of this study is to evaluate the effect of entospletinib (ENTO) on the best overall response rate in adults with chronic graft versus host disease (cGVHD) who are currently receiving systemic corticosteroids as part of first-line therapy for cGVHD.
Timeline
- Start
- 2016-05-27
- Primary completion
- 2017-12-19
- Completion
- 2018-03-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Entospletinib | Small molecule | 200 mg | Oral |
| Subject | Entospletinib | Small molecule | 400 mg | Oral |