drugset / Trial / NCT02703571
Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
Phase Ib dose escalation in advanced solid tumors to identify dose for Phase II dose expansion in advanced or metastatic pancreatic cancer and KRAS-mutant colorectal cancer. Open-label, nonrandomized.
Timeline
- Start
- 2016-06-29
- Primary completion
- 2019-09-24
- Completion
- 2019-09-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ribociclib | Small molecule | — | — |
| Subject | Trametinib | Small molecule | — | — |