drugset / Trial / NCT02704013

Urinary Biomarkers in Overactive Bladder in Children

NCT02704013

NaSingle-groupOpen-labelDiagnostic

Summary

It is a single-center, prospective, interventional, single-arm study. Aim is to investigate which variables are significantly correlated with prolonged anticholinergic treatment (\>6 months) in children with overactive bladder (OAB). Investigated variables will include urinary neurotrophins and inflammatory cytokines, sonographic biomarkers, symptom score scale, demographics, and urodynamic findings. Secondary aim is to analyze sensitivity and specificity of urinary biomarkers in diagnosis and management of OAB compared to urodynamics and treatment outcome.

Timeline

Start
2016-04
Primary completion
2017-12
Completion
2017-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxybutynin Small molecule 0.2 mg/kg Oral
Subject Oxybutynin Small molecule 0.5 mg/kg Oral

Indications