drugset / Trial / NCT02704013
Urinary Biomarkers in Overactive Bladder in Children
Unknown
50 enrolled
Children's Hospital Zagreb
University Hospital for Infectious Diseases, Croatia · collab
NaSingle-groupOpen-labelDiagnostic
Summary
It is a single-center, prospective, interventional, single-arm study. Aim is to investigate which variables are significantly correlated with prolonged anticholinergic treatment (\>6 months) in children with overactive bladder (OAB). Investigated variables will include urinary neurotrophins and inflammatory cytokines, sonographic biomarkers, symptom score scale, demographics, and urodynamic findings. Secondary aim is to analyze sensitivity and specificity of urinary biomarkers in diagnosis and management of OAB compared to urodynamics and treatment outcome.
Timeline
- Start
- 2016-04
- Primary completion
- 2017-12
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oxybutynin | Small molecule | 0.2 mg/kg | Oral |
| Subject | Oxybutynin | Small molecule | 0.5 mg/kg | Oral |