Mesenchymal Stem Cells Transplantation for Liver Cirrhosis Due to HCV Hepatitis

Summary

In this study, investigators aimed to transplant autologous, adipose tissue derived mesenchymal stem cells to the patients with liver cirrhosis due to HCV. We also aimed to assess liver tissue regeneration, downgrade of clinical findings and antiviral efficacy. Finally investigators aimed to establish an alternative treatment modality to liver transplantation.

Timeline

Start

2016-01

Primary completion

2017-07

Completion

2017-12

Publications

• Results Kantarcioglu M, Demirci H, Avcu F, Karslioglu Y, Babayigit MA, Karaman B, Ozturk K, Gurel H, Akdogan Kayhan M, Kacar S, Kubar A, Oksuzoglu G, Ural AU, Bagci S. Efficacy of autologous mesenchymal stem cell transplantation in patients with liver cirrhosis. Turk J Gastroenterol. 2015 May;26(3):244-50. doi: 10.5152/tjg.2015.0074.
• Results Kantarcioglu M, Caliskan B, Demirci H, Karacalioglu O, Kekilli M, Polat Z, Gunal A, Akinci M, Uysal C, Eksert S, Gurel H, Celebi G, Avcu F, Ural AU, Bagci S. The efficacy of mesenchymal stem cell transplantation in caustic esophagus injury: an experimental study. Stem Cells Int. 2014;2014:939674. doi: 10.1155/2014/939674. Epub 2014 May 4.

Drugs

Indications