Molecular Mechanisms of Antipsychotic-induced Insulin Resistance

Summary

This study will investigate the molecular mechanisms of atypical-antipsychotic induced insulin resistance. This will be accomplished by administering olanzapine or placebo to healthy subjects for 7 days and analyzing genetic and protein changes in peripheral tissues known to play an important role in insulin resistance pathophysiology.

Timeline

Start

2017-02-01

Primary completion

2023-10-01

Completion

2023-10-01

Drugs

Indications

No indication recorded.