drugset / Trial / NCT02708849

The Sustained Effects of Ketamine

NCT02708849

Phase 1 Terminated 3 enrolled Yale University
RandomizedParallel-groupDouble-blindBasic science

Summary

The purpose of the study is to characterize the effects of a single, sub-anesthetic dose of ketamine in rs-fMRI in healthy subjects. Post-ketamine rs-fMRI data will demonstrate a pattern of increased global brain connectivity (GBC) in fronto-temporal cortex.

Timeline

Start
2015-06
Primary completion
2020-03
Completion
2020-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.58 mg/kg Intravenous
Subject Lamotrigine Small molecule 300 mg Oral

Indications