drugset / Trial / NCT02711176

Comparison of Daily Single Dose Triple and Conventional Triple Therapies for Helicobacter Pylori Infection

NCT02711176

Phase 4 Completed 212 enrolled Zahra Vahdat Shariatpanahi
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is conducted to investigate whether the efficacy of single-dose triple therapy (Esomeprazole 40 mg, Tinidazole 1 g, and Levofluxacine 500 mg) for 14 days is superior to double-dose lansoprazole 30 mg, amoxicillin 1 g and clarithromycin 500 mg for 14 days in the treatment of H pylori infection.

Timeline

Start
2016-09
Primary completion
2017-03-27
Completion
2017-03-27

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amoxicillin Other / unclassified 1 g
Comparator Clarithromycin Small molecule 500 mg
Subject Esomeprazole Small molecule 40 mg
Comparator Omeprazole Other / unclassified 30 mg
Subject Tavanex Unknown 500 mg
Subject tinidazole Small molecule 1 g