drugset / Trial / NCT02735694

Cycloserine in the Treatment of Sleep Apnea

NCT02735694 ↗

RandomizedCrossoverTriple-blindTreatment

Summary

This study is being conducted to determine whether cycloserine is effective for the treatment of sleep apnea. Cycloserine is an antibiotic that has been extensively used in the treatment tuberculosis. However, more recently it was shown to enhance memory responses. Cycloserine may enhance the response of respiratory muscles to apnea and potentially reduce the severity of sleep disordered breathing.

Timeline

Start
2015-09
Primary completion
2016-06
Completion
2016-11

Outcome

Outcome not reported

Stopped: “Analysis of initial sample shows negative results.”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cycloserine Small molecule 250 mg Oral

Indications