Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia

Phase 4 Completed 22 enrolled Shanghai Mental Health Center University of Massachusetts, Worcester · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this research is to observe the efficacy of Naltrexone and Bupropion combination on weight loss and smoking cessation from baseline to week 24 compare to placebo.

Timeline

Start: 2016-05
Primary completion: 2018-07
Completion: 2018-07

Publications

Lyu X, Du J, Zhan G, Wu Y, Su H, Zhu Y, Jarskog F, Zhao M, Fan X. Naltrexone and Bupropion Combination Treatment for Smoking Cessation and Weight Loss in Patients With Schizophrenia. Front Pharmacol. 2018 Mar 5;9:181. doi: 10.3389/fphar.2018.00181. eCollection 2018.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupropion	Small molecule	300 mg	—
Subject	Naltrexone	Small molecule	25 mg	—

Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia

Summary

Timeline

Publications

Drugs

Indications