drugset / Trial / NCT02739594

Comparison of Ibandronate - Zoledronate Regarding Nephrotoxicity in Multiple Myeloma

NCT02739594

Phase 3 Terminated 89 enrolled Hoffmann-La Roche Roche Pharma AG · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This multicenter, open-label trial will randomize participants with multiple myeloma to a regimen of ibandronate or zoledronate in order to compare the incidence of nephrotoxicity, measured as creatinine clearance (CrCl) reduction greater than (\>) 30 percent (%) or an absolute value of 30 milliliters per minute (mL/min) or lower.

Timeline

Start
2006-02
Primary completion
2009-04
Completion
2009-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Ibandronate Other / unclassified 6 mg Intravenous
Comparator Zoledronate Other / unclassified 4 mg Intravenous

Indications