drugset / Trial / NCT02739594
Comparison of Ibandronate - Zoledronate Regarding Nephrotoxicity in Multiple Myeloma
RandomizedParallel-groupOpen-labelTreatment
Summary
This multicenter, open-label trial will randomize participants with multiple myeloma to a regimen of ibandronate or zoledronate in order to compare the incidence of nephrotoxicity, measured as creatinine clearance (CrCl) reduction greater than (\>) 30 percent (%) or an absolute value of 30 milliliters per minute (mL/min) or lower.
Timeline
- Start
- 2006-02
- Primary completion
- 2009-04
- Completion
- 2009-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ibandronate | Other / unclassified | 6 mg | Intravenous |
| Comparator | Zoledronate | Other / unclassified | 4 mg | Intravenous |