drugset / Trial / NCT02743949
Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI)
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to determine the effect of vonoprazan compared to esomeprazole for preventing heartburn symptoms over a 4-week treatment period in participants who have a partial response to treatment with esomeprazole.
Timeline
- Start
- 2016-07-14
- Primary completion
- 2018-10-05
- Completion
- 2018-10-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esomeprazole | Small molecule | 40 mg | Oral |
| Subject | Vonoprazan | Other / unclassified | 20 mg | Oral |
| Subject | Vonoprazan | Other / unclassified | 40 mg | Oral |