Multiple Ascending Dose Study of GMC-252-L-Lys Salt in Healthy Subjects and Type 2 Diabetics

Summary

The purpose of this study is to assess the safety, tolerability and pharmacokinetics (PK) of multiple oral doses of GMC-252-L-Lysine salt (GMC-252) in healthy subjects and type 2 diabetics. The secondary objective is to explore the effect of multiple oral doses of GMC-252 on pharmacodynamic(PD) parameters in type 2 diabetics.

Timeline

Start

2016-04

Primary completion

2017-09

Completion

2017-09

Outcome

Outcome not reported

Stopped: “It was considered by the sponsor that the study objective has been met by dosing 13 instead of 15 patients”

Drugs

Indications