drugset / Trial / NCT02745756
A Combined Cell Therapy Approach to the Treatment of Neuroblastoma
Phase 1
Withdrawn
H. Lee Moffitt Cancer Center and Research Institute
Johns Hopkins All Children's Hospital · collab
NaSingle-groupOpen-labelTreatment
Summary
This study adds an experimental treatment with another type of cells, called dendritic cells. It is hoped that these cells may stimulate the immune system to react against neuroblastoma in much the same way that vaccines cause the immune system to react to certain viruses and bacteria. The physicians conducting this study have observed from previous research that neuroblastoma cells can be recognized by the immune system, and that they can be destroyed by immune cells.The main goal of this study is to see if giving participants this additional anti-Neuroblastoma vaccine reduces the risk of relapse following the Hematopoietic Stem Cell Transplant.
Timeline
- Start
- 2016-04-14
- Primary completion
- 2017-08-21
- Completion
- 2017-08-21
Outcome
Outcome not reported
Stopped (Enrollment): “no enrollment”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dendritic Cell (DC) Vaccine | Vaccine | 0.5 ml | Intravenous |