drugset / Trial / NCT02748135

A Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma

NCT02748135

Phase 1 Completed 18 enrolled Oncurious NV Beat Childhood Cancer · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety and tolerability profile of TB-403 (humanized monoclonal antibody against placental growth factor (PlGF)) in pediatric subjects with relapsed or refractory Medulloblastoma.

Timeline

Start
2016-05
Primary completion
2020-10-06
Completion
2020-10-06

Drugs

EvaluationDrugModalityDoseRoute
Subject TB-403 Unknown 20 mg/kg Intravenous
Subject TB-403 Unknown 50 mg/kg Intravenous
Subject TB-403 Unknown 100 mg/kg Intravenous
Subject TB-403 Unknown 175 mg/kg Intravenous

Indications