A Phase I Study With LEO 32731 and Midazolam in Healthy Male Subjects

Summary

The purpose of this study is to investigate the effects of multiple oral doses of LEO 32731 on the pharmacokinetics of a single oral dose of the cytochrome P450 3A substrate midazolam in healthy male subjects.

Timeline

Start

2016-04

Primary completion

2016-05

Completion

2016-05

Outcome

Outcome not reported

Stopped: “Due to tolerability issues related to the dose titration, unexpected withdrawals were observed and it was unlikely for the trial to meet its objectives”

Drugs

Indications