Clinical Study of Medicinal Product Cardionat® Using in Health Athlete Volunteers

Summary

The objective of this study is to evaluate the long-term plasma and urine pharmacokinetic parameters of Cardionat®, capsules 250 mg, when used in healthy athlete volunteers. The study consists of four steps: * Step 1. Screening - selecting healthy volunteers for inclusion in the study; * Step 2. Assignment in one of the study group, prescription of the study drug; * Step 3. Samples collections for pharmacokinetic analysis; * Step 4. Evaluation of pharmacokinetic data.

Timeline

Start

2016-11

Primary completion

2019-09-25

Completion

2019-10-25

Publications

• Background Rabin O, Uiba V, Miroshnikova Y, Zabelin M, Samoylov A, Karkischenko V, Semyonov S, Astrelina T, Razinkin S. Meldonium long-term excretion period and pharmacokinetics in blood and urine of healthy athlete volunteers. Drug Test Anal. 2019 Apr;11(4):554-566. doi: 10.1002/dta.2521. Epub 2018 Nov 12.

Drugs

Indications