Effect of Banaba (Lagerstroemia Speciosa) on Metabolic Syndrome, Insulin Secretion and Insulin Sensitivity

Summary

The Metabolic Syndrome is a high prevalence disease worldwide. About a quarter of the adult population suffers the disease. Banaba has shown evidence that has on metabolic syndrome, insulin sensitivity and insulin secretion. The investigators hypothesis was that the the administration of resveratrol modifies the metabolic syndrome, insulin sensitivity and insulin secretion.

Timeline

Start

2015-01

Primary completion

2016-12

Completion

2017-02

Outcome

Mixed primary results

registry MEAN Banaba: 148.0 (Standard Deviation 43.0) mg/dL NCT02767869 ↗

registry MEAN Placebo: 199.9 (Standard Deviation 101.9) mg/dL NCT02767869 ↗

registry analysis (unspecified test); Banaba vs Placebo; p = 0.021; Wilcoxon (Mann-Whitney) NCT02767869 ↗

registry MEAN Banaba: 56.4 (Standard Deviation 11.2) mg/dL NCT02767869 ↗

registry MEAN Placebo: 58.4 (Standard Deviation 16) mg/dL NCT02767869 ↗

registry analysis (unspecified test); Banaba vs Placebo; p = 0.530; Wilcoxon (Mann-Whitney) NCT02767869 ↗

Publications

• Lopez-Murillo LD, Gonzalez-Ortiz M, Martinez-Abundis E, Cortez-Navarrete M, Perez-Rubio KG. Effect of Banaba (Lagerstroemia speciosa) on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion. J Med Food. 2022 Feb;25(2):177-182. doi: 10.1089/jmf.2021.0039. Epub 2021 Nov 2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Banaba	Unknown	500 mg	—

Indications