drugset / Trial / NCT02768337
Cambridge Brain Mets Trial 1
Phase 1/2
Terminated
26 enrolled
Cambridge University Hospitals NHS Foundation Trust
Boehringer Ingelheim · collabCancer Research UK · collabThe Brain Tumour Charity · collabUniversity of Cambridge · collab
RandomizedParallel-groupOpen-labelOther
Summary
Proof of principle phase 1b / randomised phase 2 study of afatinib penetration into cerebral metastases for patients undergoing neurosurgical resection, both with and without prior low-dose, targeted radiotherapy.
Timeline
- Start
- 2015-03-10
- Primary completion
- 2020-08-12
- Completion
- 2021-08-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Afatinib | Small molecule | — | — |