Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch

Summary

The purpose of this project is to investigate the effect of capsaicin-induced neurogenic inflammation with three different intensities on itch subsequently induced by histamine and cowhage. The hypothesis is that capsaicin-induced pre-established neurogenic inflammation significantly increases susceptibility to itch provocations with cowhage and histamine.

Timeline

Start

2016-05

Primary completion

2016-07

Completion

2016-07

Drugs

Indications

No indication recorded.