drugset / Trial / NCT02787915

DC1s-CTL Cellular Therapy for Renal Cell Carcinoma

NCT02787915 ↗

Phase 1/2 Unknown 50 enrolled Xuzhou Medical University
NaSingle-groupOpen-labelTreatment

Summary

This trial is to evaluate the safety and effectiveness of autologous type-1 polarized dendritic cell vaccines (patients' autologous DC1s loaded with multiple antigens CTL epitope peptide complexes), after radical resection for patients with stage III-IV renal cell carcinoma. Autologous cytotoxic of T lymphocytes (CTL) induced by type-1 polarized dendritic cells (DC1) loaded with MAGE-3/MAGE-4/survivin/ her2 /COX-2 CTL epitope peptides .

Timeline

Start
2016-09
Primary completion
2019-08
Completion
2019-08

Drugs

EvaluationDrugModalityDoseRoute
Subject CTL Cell therapy — Intravenous
Subject DC1 Unknown 3e+06 cells Subcutaneous

Indications