drugset / Trial / NCT02787915
DC1s-CTL Cellular Therapy for Renal Cell Carcinoma
NaSingle-groupOpen-labelTreatment
Summary
This trial is to evaluate the safety and effectiveness of autologous type-1 polarized dendritic cell vaccines (patients' autologous DC1s loaded with multiple antigens CTL epitope peptide complexes), after radical resection for patients with stage III-IV renal cell carcinoma. Autologous cytotoxic of T lymphocytes (CTL) induced by type-1 polarized dendritic cells (DC1) loaded with MAGE-3/MAGE-4/survivin/ her2 /COX-2 CTL epitope peptides .
Timeline
- Start
- 2016-09
- Primary completion
- 2019-08
- Completion
- 2019-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CTL | Cell therapy | — | Intravenous |
| Subject | DC1 | Unknown | 3e+06 cells | Subcutaneous |