drugset / Trial / NCT02791191

A Study of LY3202626 on Disease Progression in Participants With Mild Alzheimer's Disease Dementia

NCT02791191 ↗

Phase 2 Terminated 316 enrolled Eli Lilly and Company
RandomizedParallel-groupTriple-blindTreatment

Summary

The main purpose of this study is to evaluate the safety and the effect on brain tau of the study drug LY3202626 in participants with mild Alzheimer's disease (AD) dementia.

Timeline

Start
2016-06-16
Primary completion
2018-07-02
Completion
2018-07-02

Outcome

Missed primary endpoint

Stopped: “Low likelihood of identifying a statistically significant treatment effect.”

registry analysis (superiority test); 3 mg LY3202626 vs Placebo; p = 0.418; ANCOVA NCT02791191 ↗

registry analysis (superiority test); 12 mg LY3202626 vs Placebo; p = 0.231; ANCOVA NCT02791191 ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject LY3202626 Unknown 3 mg Oral
Subject LY3202626 Unknown 12 mg Oral

Indications