Progevera 10 mg® Versus Orgalutran® in Ovarian Stimulation Cycles of Oocyte Donors

Summary

Evaluation of efficacy and safety of medroxiprogesterone acetate (Progevera 10 mg®) versus GnRh antagonist (Orgalutran®) in ovarian stimulation cycles of oocyte donors

Timeline

Start

2016-06

Primary completion

2017-07

Completion

2017-07-10

Outcome

Met primary endpoint

paper 95% CI of the difference -2.78, -1.83 excluding the pre-defined non-inferiority limit (-3). PMID 30927417 ↗

Publications

• Begueria R, Garcia D, Vassena R, Rodriguez A. Medroxyprogesterone acetate versus ganirelix in oocyte donation: a randomized controlled trial. Hum Reprod. 2019 May 1;34(5):872-880. doi: 10.1093/humrep/dez034.

Drugs

Indications