A Study of Single and Repeated Doses of Glucagon Administered to Participants With Diabetes

Summary

This study will investigate how the body processes nasal glucagon and the effect of nasal glucagon on the body. After an 8-hour overnight fast and 4 hours after the start of a low-carbohydrate breakfast, the study drug will be delivered into the participant's nostril(s) (intranasally) once or twice in each of four study periods. The study is open to adults with type 1 or type 2 diabetes and is expected to last about 50 days for each participant.

Timeline

Start

2014-06

Primary completion

2014-06

Completion

2014-08

Outcome

Outcome not reported

Stopped: “Drug delivery was below target dose due to partial obstruction by aggregated particles.”

Drugs

Indications