Effectiveness of Bifidobacteria in Children Affected by Seasonal Allergic Rhinitis

Summary

This study is aimed at assessing the efficacy of supplementation with a mixture of three bifidobacteria , on the allergic rhinitis..The rhinitis symptoms were assessed by validated score ( TSS ) , for children aged between 4 and 17 years with allergic rhinitis parietaria , mild , moderate or severe , than children not supplemented . Secondary Objectives * The effectiveness of treatment by VAS : * Evaluation of the rescue medication consumption * Evaluation of quality of life ( using structured questionnaire ) * Evaluation of the frequency and school performance ( using structured questionnaire ) * Assessment of sleep quality and attention (through structured questionnaire ) * Satisfaction rating and satisfaction of parents * Evaluation of asthma exacerbations in children susceptible

Timeline

Start

2016-12

Primary completion

2018-07

Completion

2019-07

Publications

• Miraglia Del Giudice M, Indolfi C, Capasso M, Maiello N, Decimo F, Ciprandi G. Bifidobacterium mixture (B longum BB536, B infantis M-63, B breve M-16V) treatment in children with seasonal allergic rhinitis and intermittent asthma. Ital J Pediatr. 2017 Mar 7;43(1):25. doi: 10.1186/s13052-017-0340-5.

Drugs

Indications