drugset / Trial / NCT02808455

Study to Assess the Relative Bioavailability of Pacritinib Following Oral Administration as Capsule and Solution Formulations in Healthy Subjects

NCT02808455

Phase 1 Completed 12 enrolled CTI BioPharma Covance · collab
RandomizedCrossoverOpen-labelOther

Summary

This was a randomized, 2-period, 2-treatment-sequence crossover study to determine the relative bioavailability of pacritinib following administration as a 400 mg oral dose of four 100 mg pacritinib capsules and an 80 mg dose of an oral solution and to characterize the PK and major human metabolites of pacritinib.

Timeline

Start
2015-01
Primary completion
2015-03
Completion
2015-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Pacritinib Small molecule 80 mg Oral
Subject Pacritinib Small molecule 400 mg Oral

Indications

No indication recorded.