drugset / Trial / NCT02818036
An fMRI Study of Opioid-related Changes in Neural Activity
RandomizedParallel-groupDouble-blindBasic science
Summary
The purpose of the study is to explore the effect of blocking opioids on affiliation-related neural activity.
Timeline
- Start
- 2016-08
- Primary completion
- 2018-06-21
- Completion
- 2018-06-21
Publications
- Ross LP, Andreescu C, Inagaki TK. Relationships Between Early Maternal Warmth and Social Connection: A Randomized Clinical Trial With Naltrexone. Psychosom Med. 2021 Oct 1;83(8):924-931. doi: 10.1097/PSY.0000000000000986.
- Inagaki TK, Hazlett LI, Andreescu C. Opioids and social bonding: Effect of naltrexone on feelings of social connection and ventral striatum activity to close others. J Exp Psychol Gen. 2020 Apr;149(4):732-745. doi: 10.1037/xge0000674. Epub 2019 Aug 15.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naltrexone | Small molecule | 50 mg | Oral |
Indications
No indication recorded.