drugset / Trial / NCT02822534

The Pharmacokinetics and Pharmacodynamics Study of Single and Multiple Dose of SP2086 in Type 2 Diabetes Patients

NCT02822534

Phase 1 Unknown 24 enrolled Jiangsu HengRui Medicine Co., Ltd.
Non-randomizedFactorialOpen-labelTreatment

Summary

SP2086 is a novel inhibitor of Dipeptide base peptidase 4, allows an insulin-independent approach to improve type 2 diabetes hyperglycemia. In this single-dose and multiple-dose study the investigators evaluated the safety, tolerability and PK/PD profiles of SP2086 in Type 2 Diabetes Patients .

Timeline

Start
2016-04
Primary completion
2016-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Retagliptin Small molecule 50 mg
Subject Retagliptin Small molecule 100 mg
Subject Retagliptin Small molecule 200 mg