drugset / Trial / NCT02824952

Neo-adjuvant Trial With AZD9291 in EGFRm+ Stage IIIA/B NSCLC

NCT02824952

NaSingle-groupOpen-labelTreatment

Summary

Patients will receive AZD9291 at a dose of 80 mg once daily. Systemic evaluation will be done by PET-CT scan after 6 weeks. In responding patients AZD9291 will be given orally 80 mg daily for 12 weeks. Non-responding patients will receive AZD9291 for the period of 6 or 12 weeks (according to the results of response assessment at each time-point).

Timeline

Start
2018-11-01
Primary completion
2022-12
Completion
2022-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Osimertinib Small molecule 80 mg Oral