Multicenter Randomized Double Blind Controlled-study to Assess the Potential of Methotrexate Versus Placebo to Improve and Maintain Response to Anti TNF- Alpha Agents in Adult Patients With Moderate to Severe Psoriasis

Summary

The overall purpose of this trial is to assess efficacy and safety of the combination of low doses of Methotrexate (MTX) with anti Tumor Necrosis Factor (TNF) alpha to improve initial efficacy and maintenance rate of anti-TNF alpha treatment in patients with psoriasis.

Timeline

Start

2017-01-23

Primary completion

2023-01-10

Completion

2024-02-10

Outcome

Outcome not reported

Stopped (Enrollment): “new treatment on the market in direct competition with the new treatment proposed by the study. Recruitment difficulties.”

Drugs

Indications