drugset
drugset / Trial / NCT02829697

The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability

NCT02829697 ↗

Phase 4 Completed 120 enrolled Nordsjaellands Hospital Innovation Fund Denmark · collab
RandomizedParallel-groupTriple-blindTreatment

Summary

The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve and the sciatic nerve in healthy volunteers. The hypothesis is that nerve block duration is correlated to local anaesthetic volume, but only to a certain degree. After a sufficient volume a 'saturation level' will be reached, and nerve block duration will not increase further.

Timeline

Start
2016-07
Primary completion
2017-03-20
Completion
2017-03-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ropivacaine Other / unclassified 2.5 ml Other
Comparator Ropivacaine Other / unclassified 5 ml Other
Comparator Ropivacaine Other / unclassified 10 ml Other
Comparator Ropivacaine Other / unclassified 15 ml Other
Comparator Ropivacaine Other / unclassified 20 ml Other
Comparator Ropivacaine Other / unclassified 30 ml Other

Indications

No indication recorded.